Ibuprofen (Ibuprofen)

Name:Ibuprofen (Ibuprofen)

Indications for use:
• rheumatoid arthritis;
• osteoarthritis;
• ankylosing spondylitis;
• gout;
• neuralgia;
• myalgia;
• bursitis;
• sciatica;
• traumatic inflammation of soft tissues and musculoskeletal system;
• adnexitis (as part of complex therapy);
• proctitis (as part of complex therapy);
• diseases of ENT organs (as part of complex therapy);
• headache (as an aid);
• toothache (as an aid).

Pharmacological action:
It has an analgesic, anti-inflammatory and moderate antipyretic effect due to the inhibition of prostaglandin biosynthesis by inhibiting the cyclooxygenase enzyme.

After oral administration, it is rapidly absorbed from the gastrointestinal tract. The maximum plasma concentration is determined after 1-2 hours after administration, in the synovial fluid – after 3 hours after administration. Metabolized in the liver. The half-life is within 2 hours. It is excreted by the kidneys unchanged and in the form of conjugates.

Ibuprofen (Ibuprofen) method of administration and doses:
In rheumatoid arthritis, 800 mg is prescribed 3 times / day.
In osteoarthritis and ankylosing spondylitis, Ibuprofen is used at 400-600 mg 3-4 times / day.
In juvenile rheumatoid arthritis, the product is used at a dose of 30-40 mg/kg body weight/day.
For soft tissue injuries, sprains, the product is prescribed 600 mg 2-3 times / day.
With pain syndrome of moderate intensity, the product is prescribed 400 mg 3 times / day. The maximum daily dose is 2.4 g.

Ibuprofen (Ibuprofen) contraindications:
• erosive and ulcerative lesions of the gastrointestinal tract in the acute phase;
• “aspirin triad”;
• disorders of hematopoiesis;
• ulcerative colitis;
• diseases of the optic nerve;
• severe impairment of kidney and/or liver function;
• children’s age up to 6 years;
• high susceptibility to the product.

Ibuprofen (Ibuprofen) side effects:
Perhaps: nausea, anorexia, flatulence, constipation, heartburn, diarrhea, dizziness, headache, agitation, insomnia, allergic reactions in the form of a skin rash, blurred vision. There have been cases of erosive and ulcerative lesions of the gastrointestinal tract.
Rarely: bleeding from the gastrointestinal tract, aseptic meningitis, bronchospasm.

During pregnancy, the product should only be used as directed by a physician.

In overdose of ibuprofen, the following symptoms are possible: abdominal pain, nausea, vomiting, lethargy, drowsiness, depression, headache, tinnitus, metabolic acidosis, coma, acute renal failure, hypotension, bradycardia, tachycardia, atrial fibrillation and respiratory arrest .

Treatment: gastric lavage (only during the first hour after ingestion), activated charcoal (to reduce absorption), alkaline drinking, forced diuresis and symptomatic therapy (correction of acid-base balance, blood pressure, gastrointestinal bleeding).

Use with other medicinal products:
When administered concomitantly, ibuprofen may cause a decrease in the diuretic effect of furosemide.
When used together, Ibuprofen enhances the effect of diphenine, coumarin anticoagulants, oral hypoglycemic products.

Release form:
100 coated tablets of 200 mg.

Storage conditions:
Store in a dry place protected from light.

Advil, Apo-Ibuprofen, Bartel drags ibuprofen, Bonifen, Bren, Brufen, Burana, Dolgit, Ibupron, Ibuprofen, Ibuprofen Lannacher, Ibuprofen Nycomed, Ibuprofen-Teva, Ibusan, Ipren, Markofen, MIG 200, Motrin, Nurofen, Profen , Reumafen

Ibuprofen (Ibuprofen) composition:
1 tablet contains 200 mg of ibuprofen.

With caution, the product is prescribed to patients with impaired liver function, kidney disease, diseases of the cardiovascular system, with a history of gastric and / or duodenal ulcer, bleeding from the gastrointestinal tract. Compared with other NSAIDs, Ibuprofen has the least ulcerogenic effect on the gastrointestinal mucosa.
With long-term use of the product, it is necessary to monitor the function of the liver and kidneys, the picture of peripheral blood.

Before using the medication“Ibuprofen (Ibuprofen)” must be consulted with a doctor.
The instructions are provided solely for familiarization with “Ibuprofen (Ibuprofen) ».

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