Yellow capsule -nuphar lutea (l.) sm.
Botanical characteristic. Nymphaeaceae family. A perennial aquatic plant with a thick, fleshy rhizome, reaching a height of more than 1 m. The leaves are ovate, heart-shaped-lanceolate at the base, floating on the plane of the water. The flowers are large, solitary, yellow, fragrant on long pedicels. The fruit is juicy, berry-like. Blooms from June to late September.
Spreading. It is found in the European part of the USSR (with the exception of the Arctic), in the Caucasus, in Siberia, and Central Asia. It lives in backwaters, rivers and lakes.
Medicinal raw materials. Harvest rhizomes, leaves, flowers and fruits.
Chemical composition. The alkaloids nufarin and alpha-nufaridin, tannins and bitter substances, starch, and resins were found in the rhizome.
pharmacological properties. According to the laboratory of pharmacology VILR, the tincture of the plant in small doses excites, and in large doses it depresses the central nervous system. The alkaloid lutenurin isolated from the plant at a concentration of 1:1000 acts irritatingly when applied to the conjunctiva of the rabbit’s eye and when administered subcutaneously to rats, it is also curare-like. The alkaloid has a broad antimicrobial activity and inhibits the growth and development of gram-positive, including antibiotic-resistant bacteria, spore-forming and acid-fast bacteria, and some pathogenic fungi. It is also active in relation to Trichomonas.
Application. Roots and rhizomes act analgesic, anti-inflammatory, astringent, diuretic and choleretic. In folk veterinary medicine, they are used externally (locally) as an anesthetic for bruises, bedsores. It is also recommended for disorders of the gastrointestinal tract, as an anti-inflammatory and analgesic, sometimes for diseases of the bladder. The plant is poisonous, so it should be administered inside only under the supervision of a physician.
Lutenurin is produced in the form of 0.5% liniment for external use, vaginal balls and foaming tablets containing 3 mg of the product. Used topically in the form of 0.1-0.5% solutions in bidistilled water or in the form of 0.5% liniments. For trichomonas infections, liniment or vaginal balls are used.