A biennial herbaceous plant of the asteraceae (complex-flowered) family. Stems are erect or ascending, branched, 50-60 cm high. The leaves are oblong, stem-wrapped, entire, with fine ridges along the edge. The flowers are yellow, in baskets forming a paniculate or corymbose inflorescence; marginal flowers ligulate, infertile, up to 12 mm long; middle ones are tubular, bisexual, with a short 5-toothed bend. The baskets are up to 3 cm in diameter, with a bare, very sticky, multi-row wrapper, the leaves of which have splayed tips. The fruit is an achene. Blooms in June – September.
Spread. Comes from North America. On the territory of Ukraine, it grows as a weed on pastures and along roads in the Kharkiv, Dnipropetrovsk, Kirovohrad and Mykolaiv regions; gradually spreading to other regions.
Procurement and storage . For the manufacture of medicines, the aerial part (Herba Grinde-Nae) or only baskets are used. Harvested during the flowering of the plant. The collected raw materials are dried in a ventilated room, spreading them in a thin layer so that they do not stick together. Stored in tin boxes.
The plant is non -official (included in the seventh edition of the State Pharmacopoeia of the USSR).
Chemical composition . The above-ground part of the plant contains 10-12% resin, which includes diterpene acids from the labdan group (grindeliic, hydroxygrindeliic, oxogrindelic, and epoxygrindeliic), the bitterness of grindelin (alkaloid), glycosides, saponins (2%), carbohydrates, grindelol (sterol alcohol with phytosterol group), acetyl compounds, organic acids, flavonoids, phytosterol, tannin and traces of essential oil, which contains borneol and phenol.
Pharmacological properties and use. Grindelia raschaperena exhibits antispasmodic, antiseptic, expectorant and antiallergic effects. The antiblastic properties of the plant are studied. Grindelia preparations are most effective for pharyngitis, laryngitis, tracheitis and bronchitis (especially in the elderly and in children in conditions where mucus collects in the upper respiratory tract, which is difficult to remove). Grindelia products are used as an adjuvant for pulmonary emphysema, silicosis, and cough in patients with pulmonary tuberculosis. The plant also has a mild diuretic effect, which is why it is used for inflammation of the bladder. Previously, grindelia was used for some disorders of the heart, as its products reduce the number of heart contractions, increase blood pressure, eliminate arrhythmia and pain in the heart area, and improve well-being. Externally, the products of Grindelia unfurled are used as an antidote for phytodermatoses caused by some plants (Ruta graveolens, Toxicodendron radicans, Primula obconica, Primula chinensis), for allergic rashes, iritis and conjunctivitis. Grindelia rachaperena is an official plant in Great Britain, France, Portugal, Spain, India, USA, Venezuela and Brazil, where it is used to make a number of products (Astmin, Kelastmin, Melrosum, Colomba, Bronchicum). Medicinal forms and applications. Spain, India, USA, Venezuela and Brazil, where it is used to make a number of products (Astmin, Kelastmin, Melrosum, Colomba, Bronchicum). Medicinal forms and applications. Spain, India, USA, Venezuela and Brazil, where it is used to make a number of products (Astmin, Kelastmin, Melrosum, Colomba, Bronchicum). Medicinal forms and applications.
Internally – 1-2 g of dry grass powder is taken in the morning on an empty stomach and in the evening before going to bed for inflammation of the bladder;
tincture of the herb (1 part of raw material to 5 parts of 70% alcohol, infuse for 3 days) drink 40-60 drops per glass of water 3-6 times a day for bronchitis.
Externally – tincture is used for compresses (prepared as in the previous recipe, diluted with boiled water in a ratio of 1:3 before use). It should be remembered that excessive use (overdose) of grindelia products can cause gastritis and irritation of the kidneys and urinary tract.
Grindelia products are contraindicated in acute inflammatory conditions of the gastrointestinal tract.