Botanical characteristic. Umbrella family. A perennial herbaceous plant with a thick, sometimes many-headed root. Stems glabrous, straight, ribbed, up to 70 cm high. Basal leaves thrice pinnately dissected, bluish-green, 6-30 cm long, 2-8 cm wide. Stem leaves (sometimes absent) are smaller. The fruits are broadly ovate, glabrous or with short hairs.
Blossoms in June-July, fruits ripen in July-August (Fig. 13).
Spreading. It occurs in the south of Siberia, in the Yakut Autonomous Soviet Socialist Republic, the Krasnoyarsk Territory, the Irkutsk Region. This is a mountain-steppe plant growing on the slopes of hills, on large river terraces, in the steppe herbage.
Medicinal raw materials. Plant roots are used. They are dug with shovels, shaken off the ground and the roots are separated. Before drying, they are chopped into pieces 3-5 cm thick. The roots are dried in attics, under sheds or in well-ventilated rooms, spread out in a loose layer on a litter and turning over from time to time.
You can also harvest the hairy bloater. It grows from the Urals to Sakhalin, differs from the Siberian bloater in the dense pubescence of the umbrella, the leaves of the wrapper.
Chemical composition. The roots of the plant contain compounds of the coumarin series – dihydrosamidin and visnadin.
pharmacological properties. Biologically active substances of the plant have antispasmodic properties. Based on them, the product Floverin was created, which contains the sum of these 2 substances. Floverin has vasodilating properties, under experimental conditions eliminates vasospasm of the rabbit auricle caused by adrenaline, spasms of the vessels of the hind limbs caused by pituitrin, lowers blood pressure and increases coronary blood flow. It has a favorable effect on the heart: it slows down the rhythm by increasing the diastolic and reducing the duration of the systolic period, increases the voltage of the R and T waves of the electrocardiogram.
The drug has an antispasmodic effect on organs with smooth muscles: it lowers the tone and reduces the amplitude of contractions of the small intestine, relieves spasms of the smooth muscles of the intestine caused by barium chloride or acetylcholine. The mechanism of these phenomena is associated with M-cholinergic and adrenolytic effects. Floverin has low toxicity.
Application. Decoctions of the plant root and floverin are shown in practice as vasodilators.