Erythema annulare centrifugal Darya

Erythema annulare centrifugal Darya

Darier’s annular centrifugal erythema is an erythematous skin disease with a relapsing course. The disease is more common in middle-aged men.

Clinical picture

    • The appearance on the skin of the trunk, extremities of numerous coin-like non-scaly edematous spots of pinkish-reddish color, prone to eccentric growth, merging with the formation of bizarre polycyclic figures, rings, garlands, bordered by a roller-shaped edematous dense edge in the form of a cord embedded in the thickness of the skin. Similar annular spotted formations (rings within rings) may appear inside the rings. The central zone of the skin is somewhat sunken, slightly cyanotic
    • In some patients, atypical varieties are observed – vesicular, purpuric rashes, telangiectasias, etc.
    • Subjective disorders are not expressed, slight itching and burning are noted.
    • The course of the disease is paroxysmal: to replace one, completely disappearing rashes after 2-3 weeks, others are found. After a few months or years, spontaneous remission may occur. Erythema often recurs.

Research methods

    • Skin biopsy
    • Serological tests to rule out syphilis
    • A comprehensive clinical and laboratory examination is carried out in order to identify and treat diseases of the internal organs.

Differential Diagnosis

    • seborrheic eczema
    • Pityriasis rosea Zhibera
    • Erythema multiforme exudative
    • Dermatitis herpetiformis Dühring
    • granuloma annulare
    • Tertiary syphilitic roseola
    • Sarcoidosis.


    • Antibiotic therapy
    • Vitamins A, E, group B
    • Ketotifen
    • Pentoxifylline
    • In persistent cases – glucocorticoids.

The prognosis is favorable.

Synonym. Persistent erythema

ICD. L53.1 Erythema annulare, centrifugal

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