Myelodysplastic syndrome

Myelodysplastic syndrome

Myelodysplastic syndrome (MDS) is a group of pathological conditions characterized by impaired hematopoiesis in all sprouts, manifested by pancytopenia. MDS often transforms into acute leukemia or aplastic anemia. Frequency. Increasing incidence (1-2 per 100,000) in subsequent years may be due to more accurate diagnosis. The predominant age is over 65 years.

Risk factors

    • Endogenous: chromosomal and genetic disorders
    • Exogenous: prolonged contact with organic chemistry products, radiation, insolation, the use of certain drugs (for example, chloramphenicol, cytostatics).

Morphological classification