Hemolytic uremic syndrome

Hemolytic uremic syndrome

Hemolytic-uremic syndrome is a pathology of the kidneys that occurs with hemolytic anemia, thrombocytopenia and acute renal failure. They are observed mainly in babies, pregnant women and women in the postpartum period.


    • Infections (most likely Escherichia co//, 0157:H7). Endotoxemia triggers DIC with deposition of fibrin in the glomeruli and the development of acute renal failure
    • Reception of drugs
    • Mitomycin
    • Cyclosporine
    • Oral contraceptives.


    • Thrombosis of arterioles and capillaries of the glomerular apparatus
    • Fibrinoid necrosis of renal vessels
    • cortical necrosis.

clinical picture. Gastrointestinal bleeding, hematuria, oliguria and microangiopathic hemolytic anemia. Treatment is pathogenetic and symptomatic.


    • In babies, it is favorable with adequate conservative treatment (including hemodialysis)
    • In adults, it is less favorable. It is determined by the functional state of the kidneys. Most patients with mitomycin-induced hemolytic uremic syndrome die of renal failure within a few months.


    • Gasser disease
    • Gasser syndrome
    • Gassera-Carrera


ICD. D59.3 Hemolytic uremic syndrome



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