Mastocytosis is a disease characterized by the presence of purple-brown spots on the skin and the plane of internal organs as a result of the proliferation of mast cells, more often occurs in babies. The clinical picture depends on the form of the disease
- Mastocytoma is a skin tumor made up of mast cells. The course is benign, probably a complete cure by surgery
- Urticaria pigmentosa – multiple small accumulations of orange-pink or brown mast cells with a tendency to form vesicles and bullae. Has a benign character
- Systemic mastocytosis – mast cells infiltrate the bone marrow, liver, spleen, lymph nodes, gastrointestinal tract, skin and bone tissue. The course is malignant, the treatment is palliative. The lethal outcome is due to a violation of the morphological and functional structure of vital organs
- Other symptoms
- Pain syndrome – arthralgia, ossalgia
- Allergic reactions (up to the development of anaphylactic shock).
- Cutaneous mastocytosis and urticaria pigmentosa do not often require treatment. Possible surgical treatment for cosmetic purposes
- Systemic mastocytosis
- Antihistamine products
- NSAIDs (for example, acetylsalicylic acid)
- Glucocorticoids (prednisolone) – pulse therapy, the effect is doubtful
- Cromolyn sodium orally.
- Mastocytosis spotted
- Urticaria pigmentosa ICD. Q82.2 Mastocytosis