Mastocytosis is a disease characterized by the presence of purple-brown spots on the skin and the plane of internal organs as a result of the proliferation of mast cells, more often occurs in babies. The clinical picture depends on the form of the disease

    • Mastocytoma is a skin tumor made up of mast cells. The course is benign, probably a complete cure by surgery
    • Urticaria pigmentosa – multiple small accumulations of orange-pink or brown mast cells with a tendency to form vesicles and bullae. Has a benign character
    • Systemic mastocytosis – mast cells infiltrate the bone marrow, liver, spleen, lymph nodes, gastrointestinal tract, skin and bone tissue. The course is malignant, the treatment is palliative. The lethal outcome is due to a violation of the morphological and functional structure of vital organs
    • Other symptoms
    • Pain syndrome – arthralgia, ossalgia
    • Allergic reactions (up to the development of anaphylactic shock).


    • Cutaneous mastocytosis and urticaria pigmentosa do not often require treatment. Possible surgical treatment for cosmetic purposes
    • Systemic mastocytosis
    • Antihistamine products
    • NSAIDs (for example, acetylsalicylic acid)
    • Glucocorticoids (prednisolone) – pulse therapy, the effect is doubtful
    • Cromolyn sodium orally.


    • Mastocytosis spotted
    • Urticaria pigmentosa ICD. Q82.2 Mastocytosis

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