macroangiopathy diabetic

macroangiopathy diabetic

macroangiopathy diabetic– a frequent complication of diabetes mellitus with a predominant lesion of the coronary, cerebral and peripheral vessels, which largely determines the prognosis of the disease. Atherosclerosis. The frequency of atherosclerosis is significantly increased in patients with diabetes mellitus; this means that diabetes, like hypertension, smoking, hyperlipidemia, obesity, and family history, is a risk factor for atherosclerosis. It is not known whether this is the result of hyperglycemia itself, due to genetic factors, or associated with a concomitant increase in the prevalence of such risk factors for atherosclerosis as arterial hypertension and hyperlipidemia. It is suggested that increased insulin levels due to treatment of type I diabetes or insulin resistance in type II diabetes play a role in the development of atherosclerosis. Pathology of the coronary arteries occurs twice as often among patients with diabetes. Damage to the coronary vessels leads to myocardial ischemia and the development of coronary artery disease. Clinical features of coronary artery disease in patients with diabetes mellitus

    • The same frequency of development in men and women
    • High frequency of painless forms and MI, entailing the risk of sudden death
    • High incidence of postinfarction complications:
    • Cardiogenic shock
    • Chronic heart failure
    • Heart rhythm disorders
    • Mortality due to myocardial infarction during the first month is 2 times higher than that in patients who do not suffer from diabetes mellitus. The defeat of cerebral vessels makes a significant contribution to the development of diabetic encephalopathy. Peripheral vascular lesions. Typical ischemic lesions of the feet while maintaining normal pulsation. Frequent pinching: infection of the feet, poorly healing ulcers, gangrene.


  • E10.5 Insulin dependent diabetes mellitus with peripheral circulatory disorders
  •  179.2
  • Peripheral angiopathy in diseases classified elsewhere

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