Indications for use:
It is used for functional hyperbilirubinemia (increased bilirubin content in the blood), for patients with chronic diffuse liver diseases, for jaundice caused by enzymopathies (diseases associated with the absence or impaired activity of liver enzymes) and benign intrahepatic cholestasis (bile stasis), with food allergies accompanied by jaundice, as well as for the prevention and treatment of jaundice in newborns. There is evidence of the effectiveness of zixorin in the complex therapy of skin diseases (psoriasis, atopic dermatitis) and in chemotherapy of patients with tuberculosis.
Hepatoprotective (protecting liver tissue) agent. Induces oxidase enzymatic activity of liver microsomes; enhances the formation of glucuronides, promotes the excretion of endogenous and exogenous metabolites (metabolic products), increases the secretion of bile. The drug acts relatively selectively on microsomal enzymes, it does not have other pronounced pharmacological effects.
Zixorin (Zixorin) method of administration and doses: Zixorin is
prescribed for adults (during or after meals) for chronic diseases, 0.4-0.6 g (4-6 capsules) 1 time per week or 0.1 g 3 times everyday. The course of treatment – 2 weeks. After a 2-4 week break, it is possible to repeat the course using the same dose or reduced, depending on the condition of the patient.
With jaundice, newborns are given from the 2nd day of life at 10 mg / kg every day for 3-5 days. For the prevention of jaundice in newborns, a pregnant woman is given 1-3 days before the expected birth of 0.4 g (4 capsules) once.
With atopic dermatitis in babies, zixorin is prescribed at 2 mg / kg in 1-2 doses.
It should be borne in mind that due to the induction (activation) of liver enzymes, zixorin can accelerate the metabolism (decomposition) of other drugs used simultaneously.