Indications for use:
Used in complex therapy: Rheumatology: rheumatoid arthritis, extra-articular rheumatism, ankylosing spondylitis, Sjögren’s disease. Angiology: thrombophlebitis, post-thrombotic syndrome, vasculitis, thromboangiitis obliterans, prevention of recurrent phlebitis, lymphedema, secondary lymphedema. Urology: inflammation of the genitourinary tract, cystitis, cystopyelitis, prostatitis. Gynecology: chronic infections, adnexitis, mastopathy. Surgery: prevention and treatment of postoperative complications (inflammation, thrombosis, edema), adhesive disease, post-traumatic and lymphatic edema, plastic and reconstructive surgery. Traumatology: injuries, fractures, distortions, dislocations, bruises, chronic post-traumatic processes, inflammation of soft tissues, injuries in sports medicine. Pulmonology: inflammation of the upper and lower respiratory tract, sinusitis, bronchitis, bronchopneumonia, bronchial asthma. Cardiology: condition after myocardial infarction (to improve the rheological properties of blood), coronary heart disease. Gastroenterology: pancreatitis, hepatitis, pancreatitis, ulcerative colitis, Crohn’s disease. Nephrology: pyelonephritis, glomerulonephritis. Endocrinology: diabetic angiopathy, diabetic retinopathy, autoimmune thyroiditis. Dermatology: atopic dermatitis, acne. Neurology: multiple sclerosis. Wobenzym is recommended to prevent infectious complications and improve the quality of life during chemotherapy or radiation therapy for cancer. During surgical interventions in order to prevent infectious complications and adhesive disease. In order to prevent the development of viral infections and their complications. Prevention of microcirculation disorders, post-stress disorders, as well as disruption of adaptive mechanisms. Prevention of side effects of hormone replacement therapy, hormonal contraception.

Pharmachologic effect:
Wobenzym is a combination of highly active enzymes of plant and animal origin with immunomodulatory, anti-inflammatory, anti-edematous, fibrinolytic and secondary analgesic effects. Enzymes (enzymes) are the basis of the body’s vital activity and take part in almost all biological processes of the body. Decreased enzyme activity often leads to acute and chronic diseases. Wobenzym has a positive effect on the course of the inflammatory process, limits the pathological manifestation of autoimmune and immunocomplex processes, and has a positive effect on the parameters of the body’s immunological reactivity. Carries out stimulation and regulation of the level of functional activity of monocytes-macrophages, natural killer cells, stimulates antitumor immunity, cytotoxic T-lymphocytes, phagocytic activity of cells. Under the influence of Wobenzym, the number of circulating immune complexes decreases and the membrane deposits of immune complexes are removed from tissues. Wobenzym accelerates the lysis of toxic metabolic products and necrotic tissues. Improves resorption of hematomas and edema, normalizes the permeability of vessel walls. Normalizes blood viscosity and microcirculation. Improves the supply of tissues with oxygen and nutrients. Wobenzym reduces the concentration of thromboxane and platelet aggregation. Regulates the adhesion of blood cells, increases the ability of erythrocytes to change their shape by regulating their plasticity, normalizes the number of normal discocytes and reduces the total number of activated forms of platelets, normalizes blood viscosity, reduces the total number of microaggregates, thus improving microcirculation and rheological properties of blood, as well as supplying tissues with oxygen and nutrients. Wobenzym reduces the side effects associated with taking hormonal products. The secondary analgesic effect of Wobenzym is manifested through the impact on the causative factors of an acute inflammatory process. Wobenzym normalizes lipid metabolism, reduces the synthesis of endogenous cholesterol, increases the content of high density lipoproteins, reduces the level of atherogenic lipids, improves the absorption of polyunsaturated fatty acids. Wobenzym increases the concentration of antibiotics in the blood plasma and inflammation, thus increasing the effectiveness of their use. At the same time, enzymes reduce unwanted side effects of antibiotic therapy.

Wobenzym (Wobenzym) method of administration and dose:
Depending on the duration and severity of the disease, at the beginning of treatment, a dose of 5 to 10 tablets 3 times every day is recommended. The maintenance dose is 3 to 5 tablets every day. The course dose of the product is selected individually. The drug is recommended to be taken at least 30 minutes before meals with plenty of water (200 ml). In order to increase the effectiveness of antibiotics and prevent dysbacteriosis, Wobenzym should be used throughout the course of antibiotic therapy at a dose of 5 tablets 3 times every day. After stopping the course of antibiotics to restore the microflora (biocenosis) of the intestine, Wobenzym should be prescribed 2-3 tablets 3 times every day for 2 weeks. As a “cover” therapy during chemotherapy and radiation therapy, Wobenzym should be used at a dose of 3-5 tablets 3 times every day until the completion of the course of chemotherapy and radiation therapy. When using Wobenzym for prophylactic purposes, the dose of the product is 2-3 tablets 3 times every day, the course is 1.5 months, repeated 2-3 times a year. Tablets should be taken at least 30 minutes before meals, without chewing, with water (150 ml).

Wobenzym (Wobenzym) contraindications:
Individual intolerance to the product. Diseases associated with an increased likelihood of bleeding (hemophilia, thrombocytopenia, etc.). Precautions and special instructions: In the case of infectious processes, Wobenzym does not replace antibiotics, but increases their effectiveness by increasing the concentration in the blood plasma and inflammation. Pregnancy and lactation are not a contraindication for the use of the product, however, pregnant women should take Wobenzym under medical supervision. According to a study by the Anti-Doping Center of the State Committee for Sports of the Russian Federation, no doping compounds were detected in the Wobenzym product. Drug Interactions: When Wobenzym is taken concomitantly with other drugs, cases of incompatibility are unknown. Increases the concentration of antibiotics in the blood plasma and inflammation.

Wobenzym (Wobenzym) side effects:
Wobenzym is well tolerated by patients. In most cases, side effects were not observed even with long-term treatment with high doses. In some cases, there are slight changes in the consistency and smell of feces, skin rashes in the form of urticaria. The drug does not adversely affect driving a car and performing work that requires a high rate of mental and physical reactions. If other adverse reactions occur that are not noted in the instructions, it is recommended to stop taking the product and consult a doctor.

Release form:
Wobenzym tablets (pellets) orange, enteric-coated, in a pack of 40, 200 or 800 pcs.


Storage conditions:
In a cool dry place. The shelf life is 3 years.

Wobenzym (Wobenzym) composition:
1 tablet Wobenzym contains 250 mg of proteolytic enzymes from pineapple and papaya plants and from the pancreas of animals: pancreatin 100 mg, papain 60 mg, bromelain 45 mg, trypsin 24 mg. chymotrypsin 1 mg, amylase 10 mg, lipase 10 mg, rutin 50 mg in one tablet. The main inactive ingredients are lactose, corn starch, magnesium stearate, stearic acid, purified water, colloidal silicone (dioxide), talc, sucrose.

Wobenzym is manufactured by `MUCOS PHARMA`, Germany.

Before using the medication“Wobenzym (Wobenzym)” should be consulted with a doctor.
The instructions are provided solely for familiarization with “Wobenzym (Wobenzym) “.

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