Salazosulfapyridinum

Name:Salazosulfapyridinum (Salazosulfapyridinum)

Indications for use:
Nonspecific ulcerative colitis, rheumatoid arthritis (an infectious-allergic disease from the group of collagenoses, characterized by chronic progressive inflammation of the joints).

Pharmacological action:
The drug has an antibacterial effect against diplococci, streptococci, gonococci, Escherichia coli. A feature of the product is that it has a pronounced therapeutic effect in patients with ulcerative colitis (chronic inflammation of the colon with the formation of ulcers caused by unclear reasons). The mechanism of this action is not fully understood. A certain role is played by the ability of the product to accumulate in the connective tissue (including intestinal tissue) and gradually separate 5-aminosalicylic acid and sulfapyridine, which have anti-inflammatory and antibacterial properties.

Salazosulfapyridinum (Salazosulfaliridine) method of administration and dose:
Before prescribing a product to a patient, it is desirable to determine the susceptibility of the microflora to it that caused the disease in this patient. Assign inside. It is recommended on the 1st day for adults 1 tablet (0.5 g) Phrase every day (at regular intervals), on the 2nd day – 2 tablets 4 times and on the following days in case of good tolerance of the product – 3 times 4 tablets 4 times every day. After subsiding of the clinical symptoms of the disease, maintenance doses (1.5-2.0 g per day) are prescribed for several months.
For children, salazosulfapyridine is prescribed in smaller doses: at the age of 5-7 years – 1/2-1 tablet (0.25-0.5 g) 3-6 times a day, over 7 years old – 1 tablet (0.5 g ) 3-6 times a day.
Salazosulfapyridine is also effective in mild to moderate forms of Crohn’s disease (a disease of unknown cause, characterized by inflammation and narrowing of the lumen of individual sections of the intestine).
Salazosulfapyridine is also used as a basic agent in the treatment of rheumatoid arthritis due to the presence of immunocorrective properties in the product (restoring immunity / body defenses /). Assign 2-3 g every day (40 mg / kg every day) for 2-6 months.
Tablets are recommended to be taken at regular intervals after meals, drink plenty of 1-2% sodium bicarbonate solution (baking soda).
Treatment should be carried out under close medical supervision; it is necessary to systematically monitor the blood picture.

Salazosulfapyridinum (Salazosulfaliridine) contraindications:
Severe toxic-allergic reactions in history (previously) to sulfonamides.

Salazosulfapyridinum (Salazosulfaliridine) side effects:
Nausea, vomiting, headache, dizziness may occur. In such cases, cancel the product, and after 2 days gradually, over 3 days, again increase the dose. Allergic reactions in the form of skin rashes, drug fever (a sharp rise in body temperature in response to taking the product); leukopenia (decrease in the level of leukocytes in the blood). In these cases, the use of the product should be discontinued. The drug is excreted in the urine and, with an alkaline reaction, stains it in a yellow-orange color.

Release form:
Tablets of 0.5 g in a pack of 50 pcs.

Synonyms:
Sulfasalazine, Azopyrin, Azufidine, Salazopyridine, Salazopyrin, Salicylazosulfapyridine, Salisulf.

Storage conditions:
List B. In a dry, dark place.

Attention!
Before using the medication“Salazosulfapyridinum (Salazosulfaliridin)” should be consulted with a doctor.
The instructions are provided solely for familiarization with “Salazosulfapyridinum .

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