Pamipril (Ramipril)

Name:Ramipril (Pamipril)

Indications for use:
Arterial hypertension (persistent rise in blood pressure); congestive heart failure; prevention of sudden death after myocardial infarction.

Pharmacological action:
Antihypertensive (lowering blood pressure) agent, angiotensin-converting enzyme inhibitor. By suppressing the synthesis of angiotensin II, it reduces its vasoconstrictor (narrowing the lumen of the vessels) effect and its stimulating effect on the secretion (release) of aldosterone. Increases plasma renin activity. The drug also inhibits the metabolism (prevents decomposition in the body) of bradykinin.
The drug reduces the total vascular peripheral resistance, does not significantly change renal blood flow (and in some cases increases it).

Pamipril (Ramipril) method of administration and doses: The
initial dose of the product is usually 0.0025 g, taken 1 time per day (in the morning) on ​​an empty stomach and washed down with water. In case of insufficient antihypertensive effect, the dose of the product after 3 weeks. gradually increase, but also appoint a one-time. In some patients, a uniform antihypertensive effect throughout the day is achieved by taking the product 2 times every day.
The maximum daily dose of the product is 0.01 g, and maintenance, as a rule, 0.0025-0.005 g.
If the effect is insufficient, it can be used in conjunction with diuretics.
In patients with diabetes mellitus and those over 65 years of age, the initial daily dose should not exceed 0.00125 g, and the largest -0.005 g.
The drug should be used with caution under the supervision of a physician.

Pamipril (Ramipril) contraindications:
Increased susceptibility to the product, stenosis (narrowing) of the renal arteries, a condition after a kidney transplant, narrowing of the aorta, hypertrophic cardiomyopathy (heart disease of an unclear or controversial origin of a non-inflammatory nature, accompanied by its increase), primary hyperaldosteronism (edema, congestion fluid in the abdominal cavity, an increase in blood pressure associated with an increased content of aldosterone), pregnancy, lactation, severe renal dysfunction, liver failure. Do not administer to children under 14 years of age.
Patients whose activities are associated with the need for a quick concentration of attention and a quick reaction (drivers of vehicles, operators, etc.) should be careful when treating with the product.
While taking the product, you should refrain from drinking alcohol.

Pamipril (Ramipril) side effects:
Hypotension (lowering blood pressure), collapse (a sharp drop in blood pressure), heart rhythm disturbances, exacerbation of coronary heart and brain disease, impaired renal function up to the development of acute renal failure (especially when taking diuretics at the same time) , proteinuria (protein in the urine), nausea, diarrhea or constipation, vomiting; neurological disorders and others.

Release form:
Tablets of 0.0025 and 0.005 g in a pack of 28 pcs.


Storage conditions:
List B. In a dry, dark place.

Before using the medication“Pamipril (Ramipril)” should be consulted with a doctor.
The instructions are provided solely for familiarization with “Pamipril (Ramipril) ».

Leave a Comment

Your email address will not be published. Required fields are marked *