Baneocin (Baneocin)

Name:Baneocin (Baneocin)

Indications for use:
In dermatology (treatment of skin diseases), the product in powder form is used to treat and prevent bacterial infections of the skin and superficial wounds, burns. With secondary bacterial infection with Herpessimplex, Herpeszoster, chicken pox. The ointment is used to treat bacterial infections of the skin and mucous membranes: contagious (transmitted from a sick person to a healthy person / contagious /) impetigo (superficial pustular skin lesions with the formation of purulent crusts), boils (purulent inflammation of the skin hair follicle that has spread to surrounding tissues), carbuncles (acute diffuse purulent-necrotic inflammation of several adjacent sebaceous glands and hair follicles) – after their surgical treatment, folliculitis (inflammation of the hair follicles) of the scalp, purulent hydradenitis (purulent inflammation of the sweat glands), multiple abscesses (abscesses) of the sweat glands, abscesses – after opening, paronychia (inflammation within the nail tissue), ecthyma (inflammatory skin disease characterized by the appearance of pustules with deep ulceration in the center), pyoderma (purulent skin inflammation); secondary infections in dermatoses (skin diseases – ulcers, eczema). For the treatment and prevention of secondary infections of wound surfaces, also in cosmetic procedures (ear lobe piercing, skin transplantation). In obstetrics and gynecology, it is used for treatment in the postoperative period for perineal ruptures and episiotomy (dissection of the perineum during childbirth to prevent its rupture), laparotomy (opening the abdominal cavity); for the treatment of mastitis (inflammation of the milk-carrying ducts of the mammary gland) during drainage, for the prevention of mastitis. In otorhinolaryngology (treatment of diseases of the ear, throat and nose), the product in the form of an ointment is used in case of secondary infections in acute and chronic rhinitis (inflammation of the nasal mucosa), otitis externa (inflammation of the external ear); for treatment in the postoperative period with interventions on the paranasal sinuses, mastoid process. In pediatric (children’s) practice, the powder of the product is used to prevent umbilical infections, as well as for bacterial diaper dermatitis (skin inflammation in infants with insufficiently frequent diaper changes). The ointment is used for the same indications as in adults. In otorhinolaryngology (treatment of diseases of the ear, throat and nose), the product in the form of an ointment is used in case of secondary infections in acute and chronic rhinitis (inflammation of the nasal mucosa), otitis externa (inflammation of the external ear); for treatment in the postoperative period with interventions on the paranasal sinuses, mastoid process. In pediatric (children’s) practice, the powder of the product is used to prevent umbilical infections, as well as for bacterial diaper dermatitis (skin inflammation in infants with insufficiently frequent diaper changes). The ointment is used for the same indications as in adults. In otorhinolaryngology (treatment of diseases of the ear, throat and nose), the product in the form of an ointment is used in case of secondary infections in acute and chronic rhinitis (inflammation of the nasal mucosa), otitis externa (inflammation of the external ear); for treatment in the postoperative period with interventions on the paranasal sinuses, mastoid process. In pediatric (children’s) practice, the powder of the product is used to prevent umbilical infections, as well as for bacterial diaper dermatitis (skin inflammation in infants with insufficiently frequent diaper changes). The ointment is used for the same indications as in adults. for treatment in the postoperative period with interventions on the paranasal sinuses, mastoid process. In pediatric (children’s) practice, the powder of the product is used to prevent umbilical infections, as well as for bacterial diaper dermatitis (skin inflammation in infants with insufficiently frequent diaper changes). The ointment is used for the same indications as in adults. for treatment in the postoperative period with interventions on the paranasal sinuses, mastoid process. In pediatric (children’s) practice, the powder of the product is used to prevent umbilical infections, as well as for bacterial diaper dermatitis (skin inflammation in infants with insufficiently frequent diaper changes). The ointment is used for the same indications as in adults.

Pharmachologic effect:
A combined topical antimicrobial product containing two bactericidal (bacteria-killing) antibiotics with a synergistic effect (enhancing each other’s action when used together). The spectrum of antimicrobial action of neomycin includes most gram-positive and gram-negative microorganisms. Bacitracin is active mainly against gram-positive microorganisms (hemolytic streptococcus, staphylococci, clostridia, Corynebacterium diphtheriae, Treponemapallidum); some gram-negative microorganisms (Neisseria, Haemophilusinfluenzae), also actinomycytes and fusobacteria. Bacitracin resistance is extremely rare. Banercin is not active against Pseudomonas, Nocardia, viruses and most fungi. Topical application of the product significantly reduces the risk of systemic sensitization (increased sensitivity of the body to the product). Tissue tolerance of baneocin is regarded as excellent; inactivation (loss of activity) of the product by biological products, blood and tissue components is not observed. Baneocin powder, promoting natural perspiration, has a pleasant cooling effect.

Baneocin (Baneocin) method of administration and doses:
Before prescribing a product to a patient, it is desirable to determine the susceptibility of the microflora to it that caused the disease in this patient. The required amount of ointment or powder is applied to the affected area; if appropriate – under the bandage (the bandage helps to increase the effectiveness of the ointment). In adults and children, the powder is used 2-4 times a day; ointment – 2-3 times a day. The daily dose of the product should not exceed 1 g. The course of treatment is 7 days. With a second course, the highest dose should be halved. In patients with burns covering more than 20% of the body surface, the powder should be used 1 time per day.
In the case of using baneocin for the prevention of mastitis, it is necessary to remove the remnants of the product from the mammary gland with boiled water and sterile cotton wool before feeding.
Patients with impaired liver and kidney function should undergo blood and urine tests, as well as an audiometric study (determination of hearing acuity) before and during intensive therapy with baneocin. The product should not be applied to the eyes. When using baneocin for the treatment of chronic dermatoses or chronic otitis media, the product promotes sensitization to other products, including neomycin.
If there is systemic absorption (absorption into the blood) of baneocin, the simultaneous administration of cephalosporin antibiotics increases the risk of nephrotoxic (damaging effects on the kidneys) side effects; the simultaneous appointment of furosemide, ethacrynic acid and aminoglycoside antibiotics increases the risk of nephro- and ototoxic (damaging effects on the kidneys and hearing organs) side effects; and the appointment of muscle relaxants and local anesthetics – disorders of neuromuscular conduction.

Baneocin (Baneocin) contraindications: Hypersensitivity
to bacitracin and / or neomycin, or other antibiotics-camaminoglycosides. Significant skin lesions. Lesions of the vestibular and cochlear system in patients with impaired renal excretory function in cases where the risk of systemic absorption (absorption into the blood) of the product is increased. Do not use the product in the external auditory canal with perforation (through defect) of the eardrum.
Caution should be exercised when using the product in patients with acidosis (acidification of the blood), severe myasthenia gravis (muscle weakness) and other diseases of the neuromuscular apparatus, since these patients have an increased risk of neuromuscular conduction disorders. Neuromuscular blockade can be eliminated by the introduction of calcium products or prozerin. Caution should be exercised when prescribing to pregnant and lactating women, especially with an increased likelihood of systemic absorption of the product, since neomycin, like other aminoglycosides, penetrates the placental barrier (the barrier between the mother and fetus). The drug should be administered with caution to patients with an indication of allergic reactions in history (case history).

Baneocin (Baneocin) side effects:
In rare cases, there is redness, dryness of the skin, skin rashes and itching at the site of application of the product. Allergic reactions are possible, proceeding according to the type of contact eczema (neuro-allergic inflammation of the skin at the site of contact with an unfavorable factor /physical, chemical, etc./). In patients with extensive damage to the skin, especially when using large doses of the product, systemic side effects may occur due to absorption of the product: damage to the vestibular (damage to the membranous labyrinth of the inner ear) and cochlear (damage to the structural element of the inner ear – “cochlea”) apparatus, nephrotoxic effects and blockade of neuromuscular conduction (conducting impulses from the nervous system to the muscles). With long-term treatment, the development of superinfection (severe,

Release form:
Powder of 6 g and 10 g in dispensers. Ointment in tubes of 20 g.

Baneocin (Baneocin) composition:
1 g of the product contains 5000 IU of neomycin sulfate and 250 IU of bacitracin.

Storage conditions:
List B. Powder – at a temperature not lower than 25 ° C in a dry, dark place. Ointment – at a temperature not lower than 25 ° C.

Attention!
Before using the medication“Baneocin (Baneocin)” must be consulted with a doctor.
The instructions are provided solely for familiarization with “Baneocin (Baneocin) ».

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