Name: Sophora thick-fruited
Perennial herbaceous plant 30-60 cm tall, legume family. The stems are traditionally branched from the base, abundantly leafy with pinnate leaves. The root system is powerful, deep-lying. The flowers are white, with a yellowish tinge, collected in narrow striped apical racemes. The fruits are brown beans, indehiscent, short, with a slight constriction in the middle, the seeds are brown, with a rounded scar, 5-6 mm long and 4-5 mm wide. Flowering in April-May, fruiting in June-July.
Grows on loess and sandy soils in the deserts and foothills of Central Asia, is a dangerous weed in wheat crops.
Medicinal raw material is grass before flowering. The herb contains 3% pachycarpine alkaloid; the seeds contain sofocarpine and matrine. For industrial purposes, grass is harvested before flowering, flowering and flowering, from which pachycarpine is obtained.
Pahikarpin is used for spasms of peripheral vessels, in particular for endarteritis, including its sclerotic forms. Assign inside of 0.05-0.1 g 2-3 times every day for 3-6 weeks. The course of treatment, if necessary, can be repeated after 2-3 months. With favorable results of treatment, the diseased limbs become warmer, the skin turns pink, pain stops or decreases, blood circulation in the diseased limb improves, and gait is facilitated. Improvement can be long – for a year or more. Deterioration can occur as a result of nervous shocks or with exacerbations of concomitant diseases.
Positive results of treatment with pachycarpine are also observed in myopathies: in patients with increased strength and range of motion, tendon reflexes are detected. The therapeutic effect is observed traditionally 10-12 days after the start of treatment. With myopathies, pahikarpine is prescribed orally at 0.1 g 2-3 times every day for 40-50 days. If necessary, the course of treatment is repeated after 1-3 months.
When using pachycarpine, side effects are possible in the form of pain in the region of the heart.
Pahikarpin is not recommended for use in diseases of the liver, kidneys, febrile illnesses, cardiac disorders, angina pectoris, pregnancy.